John Mulaney: Mister Whatever is a stand-up comedy show in which comedian John Mulaney performs material from his Mister Whatever tour at the Louisville Palace Theatre in downtown Louisville, Kentucky. The event showcases Mulaney’s signature observational storytelling and character-driven bits in a historic, large-capacity theater that regularly hosts major touring performers. It is notable as part of a high-profile comedy tour drawing significant local interest for a leading contemporary stand-up act.